We stayed at Hotel Grifo in Rome a few years ago. It's not fancy but it's nice and was clean and offered breakfast. It's a great location in the Monti area. https://www.hotelgrifo.com/en/

It's near cafes and shops and walking distance to the coliseum and many other sites.

Ilike the second one because i find it stands out better. i find the first one too pale.

I like both papers, but, think they may be too cutesy for a powder room.

I notice there are a few tones of green in the bathroom. Find a paper to include them>

https://www.spoonflower.com/en/wallpaper/19213753-ditsy-olive-mint-forest-green-white-lotus-flower-watercolor-fabric-art-deco-by-yvonnehartstudio

Aren't you in Maine? I'm somewhat of a traditionalist and I wouldn't use a tropical or color-saturated paper just because a powder room allows you to be bold. It's a Maine powder room.

I like the idea of a colored background rather than a cream background, like the blue-gray paper Emily posted. I like how the creamy white flowers pick up the color of the vanity and window trim while the background matches the floor tile. I wouldn't use that particular paper however.